Archives for Chemistry Experiments of 41979-39-9

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Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent£¬ Safety of Piperidin-4-one hydrochloride, Which mentioned a new discovery about 41979-39-9

TRICYCLIC COMPOUNDS FOR THE TREATMENT OF INFLAMMATORY DISORDERS

The present invention provides compounds represented by general formula (1) wherein, R1 R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13 and X are as defined in the specification, in all its stereoisomeric and tautomeric forms and mixtures thereof in all ratios, and its pharmaceutically acceptable salts, pharmaceutically acceptable solvates, pharmaceutically acceptable polymorphs and prodrugs. These compounds are useful for treatment of inflammatory disorders including those caused by elevated levels of proinflammatory cytokines such as Tumor Necrosis Factor (TNF-alpha and/or interleukins (IL-1beta, IL-6, IL-8). The invention also relates to processes for the manufacture of compounds of formula (1) and pharmaceutical compositions containing them.

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Reference£º
Piperidine – Wikipedia,
Piperidine | C5H5856N – PubChem