Chemistry is the science of change. But why do chemical reactions take place? Why do chemicals react with each other? The answer is in thermodynamics and kinetics, COA of Formula: C12H9N5O, 4005-49-6, Name is N-(7H-Purin-6-yl)benzamide, SMILES is O=C(NC1=C2NC=NC2=NC=N1)C3=CC=CC=C3, belongs to piperidines compound. In a document, author is Gazitua, Marcela, introduce the new discover.
Effect of the nature of the nucleophile and solvent on an SNAr reaction
The reaction of 2,4-dinitrobenzenesulfonyl chloride toward propylamine was kinetically evaluated in 19 organic solvents and 10 ionic liquids as reaction media. This study was compared with a previous study to experimentally show that solvent effects and the nature of the reacting pair drastically affect the reaction rate and the reaction mechanism. While the reaction of the reference electrophile 2,4-dinitrobenzenesulfonyl chloride with piperidine is favored in polar solvents with the ability to donate or accept hydrogen bonds, the reaction with propylamine is favored in solvents with the ability to accept hydrogen bonds.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 4005-49-6. COA of Formula: C12H9N5O.
Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem