Synthetic Route of 3466-80-6, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 3466-80-6, Name is 2-Phenylpiperidine, molecular formula is C11H15N. In a Article£¬once mentioned of 3466-80-6
Origins of Small Proton Chemical Shift Differences in Monodeuterated Methyl Groups
We have recently shown that the small proton chemical shift difference in 2-methyl-1-(methyl-d)piperidine supports a long-lived nuclear spin state. To identify additional candidate molecules with CH2D groups exhibiting accessible long-lived states, and to investigate the factors governing the magnitude of the shift differences, we report a computational and experimental investigation of methyl rotational equilibria and proton chemical shifts in a variety of 2-substituted 1-(methyl-d)piperidines. The polarity and size of the 2-substituent affect the 1,2-stereoisomeric relationship, and consequently, the strength of the rotational asymmetry within the CH2D group. Nonpolar and large 2-substituents prefer the equatorial position, and relatively large shift differences (i.e., > 13 ppb) are observed. Polar and small substituents, however, increasingly prefer the axial position, and medium to small shift differences (i.e., 0 to 9 ppb) are observed. In addition, the diastereotopic CH2D proton chemical shift difference for tricarbonyl(1-chloro-2-deuteriomethylbenzene) chromium(0) was computed, showing that reasonable predictions of these small shift differences can be extended to more complex, organometallic species.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Synthetic Route of 3466-80-6, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 3466-80-6, in my other articles.
Reference£º
Piperidine – Wikipedia,
Piperidine | C5H9245N – PubChem