Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. , Formula: C8H11N5O, 14047-28-0, Name is (R)-1-(6-Amino-9H-purin-9-yl)propan-2-ol, molecular formula is C8H11N5O, belongs to piperidines compound. In a document, author is Gressies, Steffen, introduce the new discover.
Ligand-Enabled Enantioselective C-sp3-H Activation of Tetrahydroquinolines and Saturated Aza-Heterocycles by Rh-I
The first rhodium(I)-catalyzed enantioselective intermolecular C-sp3-H activation of various saturated aza-heterocycles including tetrahydroquinolines, piperidines, piperazines, azetidines, pyrrolidines, and azepanes is presented. The combination of a rhodium(I) precatalyst and a chiral monodentate phosphonite ligand is shown to be a powerful catalytic system to access a variety of important enantio-enriched heterocycles from simple starting materials. Notably, the C-sp3-H activation of tetrahydroquinolines is especially challenging due to the adjacent C-sp2-H bond. This redox-neutral methodology provides a new synthetic route to -N-arylated heterocycles with high chemoselectivity and enantioselectivity up to 97%ee.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 14047-28-0. Formula: C8H11N5O.
Reference:
Piperidine – Wikipedia,
,Piperidine | C5H11N – PubChem