Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， Computed Properties of C11H22N2O2, Which mentioned a new discovery about 135632-53-0
The present invention provides a MDM2 – HDAC inhibitors of double-target, pharmaceutical composition and its preparation and use, the MDM2 – HDAC inhibitors have the formula I-target structure shown, the invention of the structure shown in formula I can be at the same time inhibiting the inhibitors of MDM2 and HDAC activity, promotion of apoptosis, cell growth suppression and cycle arrest, with double target spot inhibitory, can reduce the apoptosis of tumor cells threshold, and can increase the p53 acetylation level, make the p53 stability exists in the nucleoli, extended p53 half-life, the invention of the MDM2 – HDAC double-target inhibitor can protect normal cells from certain chemical and radiation the toxic effect of the therapeutic agent, for more effective treatment of cancer. (by machine translation)
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Reference：
Piperidine – Wikipedia,
Piperidine | C5H17293N – PubChem