With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.85908-96-9,N-Boc-2-Piperidone,as a common compound, the synthetic route is as follows.,85908-96-9
General procedure: To a 0.5 M solution of LiHMDS (2.75 equiv) cooled to -78 C was added dropwise a 0.75 M solution ofprotected lactam in THF. This solution was stirred for 1 h while slowly warming to rt, then cooled backdown to -78 C. Alkyl halide (5.00 equiv) was then added dropwise and the solution was left to stir whilewarming up slowly to rt until completion. A saturated aqueous solution of NH4Cl was added to thereaction mixture, then the THF was removed under reduced pressure. The resulting suspension wasdiluted in more water, then extracted with EtOAc three times. The organic layers were combined, driedwith anhydrous MgSO4, filtered and concentrated under reduced pressure
As the paragraph descriping shows that 85908-96-9 is playing an increasingly important role.
Reference：
Article; Aubert-Nicol, Samuel; Heinrich, Nora; Lessard, Jean; Spino, Claude; Heterocycles; vol. 99; 1; (2019); p. 484 – 501;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem