77211-75-7, Benzyl 1-oxa-6-azaspiro[2.5]octane-6-carboxylate is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
77211-75-7, EXAMPLE XVI 1-benzyloxycarbonyl-4-hydroxy-4-[N-methyl-N-(ethoxycarbonylmethyl)aminomethyl]piperidine A mixture of 2.7 g of sarcosine ethyl ester and 3.09 g of 6-benzyloxycarbonyl-1-oxa-6-azaspiro[2.5]octane in 20 ml of ethanol is heated to 90 C. for 6 hours in a bomb tube. After cooling overnight, the mixture is evaporated down and the residue is purified by chromatography over a silica gel column with cyclohexane/ethyl acetate (1:1). Yield: 1.8 g (25% of theory); mass spectrum (ESI+): m/z=365 [M+H]+; Rf value: 0.35 (silica gel, cyclohexane/ethyl acetate=1:1).
The synthetic route of 77211-75-7 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; Himmelsbach, Frank; Langkopf, Elke; Jung, Birgit; Blech, Stefen; Solca, Flavio; US2001/44435; (2001); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem