61869-08-7,With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.61869-08-7,(3S,4R)-3-((Benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine,as a common compound, the synthetic route is as follows.
1.0 g of oily paroxetine free base and 1.24 g of cholic acid were completely dissolved in a mixed solvent of methanol (10 mL) and acetone (40 mL) while heating to 40 C. with shaking for 30 minutes. The solution was allowed to stand at room temperature for 24 hours to obtain a salt. The salt was filtered, and dried under vacuum to yield 2.0 g of solid paroxetine cholate as a white crystal.
61869-08-7 (3S,4R)-3-((Benzo[d][1,3]dioxol-5-yloxy)methyl)-4-(4-fluorophenyl)piperidine 44274603, apiperidines compound, is more and more widely used in various fields.
Reference：
Patent; Lee, Sang Joon; Shin, Hee Jong; Ki, Min Hyo; Lee, Su Kyoung; Kim, Bok Young; Lee, Hong Woo; US2006/63747; (2006); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem