Epoxy compounds usually have stronger nucleophilic ability, because the alkyl group on the oxygen atom makes the bond angle smaller, which makes the lone pair of electrons react more dissimilarly with the electron-deficient system. Compound: 2,3-Dibromopropionic acid, is researched, Molecular C3H4Br2O2, CAS is 600-05-5, about Dissociation of halogen-substituted propionic acids in water-acetonitrile solvent mixtures. Substituent effects.Name: 2,3-Dibromopropionic acid.
The pK values of AcOH, EtCO2H and halogen-substituted EtCO2H in H2O/MeCN mixtures were determined at 25° by potentiometric titration The values for α-Cl-, β-Cl-, α-Br-, β-Br-, β-I-, α,α-di-Cl-, α,β-di-Cl-, α,β-di-Br-propionic acid, AcOH and EtCO2H in aqueous mixtures containing 0, 20, 40, 60 and 80 weight% MeCN are reported. The substituent effects on acidity are discussed.
As far as I know, this compound(600-05-5)Name: 2,3-Dibromopropionic acid can be applied in many ways, which is helpful for the development of experiments. Therefore many people are doing relevant researches.
Reference:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem