158407-04-6, tert-Butyl 4-(bromomethyl)piperidine-1-carboxylate is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A mixture of 4-hydroxy-2-methyl-6-phenoxy-9H-xanthen-9-one (33b) (100 mg, 0.31mmol), 4-bromomethyl- 1 -(tert-butoxycarbonyl)piperidine (35a) (262 mg, 0.94 mmol), K2C03 (47.8 mg, 0.35 mmol), and KI (5 mg) in IVIEK (3 mL), was heated at 70 C for 16h. The reaction was then cooled to room temperature, diluted with EtOAc, filtered and concentrated. The crude residue was filtered through a pad of silica gel, eluting with neat EtOAc to give 2-methyl-4-(( 1 -(tert-butoxycarbonyl)piperidin-4-yl)methoxy)-6-phenoxy- 9H-xanthen-9-one (35b) (159 mg, 99%), that was used directly as is in the next step.
158407-04-6, 158407-04-6 tert-Butyl 4-(bromomethyl)piperidine-1-carboxylate 15512811, apiperidines compound, is more and more widely used in various.
Reference£º
Patent; AUCKLAND UNISERVICES LIMITED; MARSHALL, Andrew James; BUCHANAN, Christina Maree; REWCASTLE, Gordon William; LU, Guo-Liang; FLANAGAN, Jack Urquhart; BONNET, Muriel; SHEPHERD, Peter Robin; JAMIESON, Stephen Michael Frazer; GAMAGE, Swarnalatha Akuratiya; DENNY, William Alexander; (213 pag.)WO2018/83635; (2018); A2;,
Piperidine – Wikipedia
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