146093-46-1, 4-(Aminoethyl)-1-N-Boc-piperidine is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Step 1 : fert-Butyl 4-(2-(dinony lamino)ethyl)piperi dine- 1-carboxy late Chemical Formula: C30H60N2O2 (2256) Molecular Weight: 480.82 (2257) [00714] a mixture of fert-butyl 4-(2-aminoethyl)piperi dine- 1 -carboxy late (1.50 g, 6.6 mmol) and 1 -bromononane (1.36 g, 6.57 mmol) in MeCN (100 mL) was added K2CO3 (1.83 g, (2258) 13.1 mmol) and KI (109 mg, 0.66 mmol) and the mixture was allowed to stir at 82 C for 12 hours. The suspension was cooled to RT, filtered over a pad of celite rinsing with hexanes, and concentrated in vacuo. Purification by ISCO silica flash chromatography (0-100% DCM/[DCM 20% MeOH 1%) NH4OH]) provided tot-butyl 4-(2-(dinonylamino)ethyl)piperidine-l – carboxylate (602 mg, 19%). (2259) UPLC/ELSD: RT = 2.41 min. MS (ES): m/z (MH+) 482 for C3oH6oN202 (2260) Ti-NMR (300 MHz, CDC13) delta: ppm 4.20-2.26 (br. m, 10H); 1.77-1.10 (br. m, 44H); 0.91 (t, (2261) 6H).
146093-46-1, The synthetic route of 146093-46-1 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; MODERNATX, INC.; BENENATO, Kerry E.; BUTCHER, William; (437 pag.)WO2017/112865; (2017); A1;,
Piperidine – Wikipedia
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