As the paragraph descriping shows that 140645-24-5 is playing an increasingly important role.
140645-24-5, (S)-3-(Aminomethyl)-1-N-Boc-piperidine is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
(1.1.1 ) (S)-tert-butyl 3-((2-chloro-5-iodopyrimidin-4-ylamino)methyl)piperidine-1- carboxylate. To a stirred solution of 2,4-dichloro-5-iodopyrimidine (3.5 g, 12.73 mmol) in THF (50 ml.) at -700C was added dropwise a solution of (SS^aminomethyl-i-piperidinecarboxylic acid- 5 (1 ,1-dimethyl)ethyl ester (3.0 g, 14 mmol) and DIEA (2.88 mL, 16.55 mmol) in THF (50 ml_). The reaction mixture was allowed to warm up to room temperature overnight. Then, the reaction mixture was diluted with EtOAc and washed with saturated NH4CI solution (2x) and brine (1x). The organic layer was dried (Na2SO4), filtered and concentrated in vacuo. The crude product was purified by column chromatography (SiO2, heptane/EtOAc; 10 100% heptane to 30% EtOAc as mobile phase) and the title compound was obtained as a white solid in 38% yield (2.19 g, 4.84 mmol). LC-MS: peak at 4.04 min., mass [M+H] = 453., 140645-24-5
As the paragraph descriping shows that 140645-24-5 is playing an increasingly important role.
Reference:
Patent; N.V. ORGANON; PHARMACOPEIA, LLC; WO2009/124965; (2009); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem