138007-24-6, tert-Butyl piperidine-4-carboxylate is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
(d) Ethyl 6-[4-(tert-butoxycarbonyl)piperidin-l-yl]-5-cyano-2-methylnicotinateA 20 mL microwave vial was charged with ethyl 6-chloro-5-cyano-2-methylnicotinate (5 g, 22.3 mmol), tert-butyl piperidine-4-carboxylate (4.11 g, 22.3 mmol), TEA (4.5 g, 44.5 mmol) and MeCN and heated, single nodeheating, to 100 0C for 5 minutes. The reaction was concentrated and MeCN/water was added to precipitate the product. Filtration of the solid and drying gave ethyl 6-[4-(tert-butoxycarbonyl)piperidin-l-yl]-5-cyano-2- methylnicotinate as an orange colored solid. Yield: 6.99 g (77percent). 1H NMR (400 MHz, DMSO-d6): delta 1.30 (3H, t), 1.40 (9H, s), 1.32-1.64 (2H, m), 1.88-1.96 (2H, m), 2.55-2.60 (IH, m), 2.63 (3H, s), 3.20-3-30 (2H, m), 4.24 (2H, q), 4.39-4.47 (2H, m), 8.31 (IH, s)., 138007-24-6
As the paragraph descriping shows that 138007-24-6 is playing an increasingly important role.
Reference£º
Patent; ASTRAZENECA AB; BYLUND, Ruth; HOVDAL, Daniel; JOHANSSON, Johan; SELLEN, Mikael; ZETTERBERG, Fredrik; WO2010/5385; (2010); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem