138007-24-6, tert-Butyl piperidine-4-carboxylate is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
(a) tert-Butyl1-(2-cyanoethanimidoyl)piperidine-4-carboxylate Two microwave vials was each charged with ethyl2-cyanoethanimidoate (See McElvain, S. M.;Schroeder, J. P.; J. Am. Chem. Soc. 71, p.40(1949)) (841 mg, 7.7 mmol), tert-butyl piperidine-4-carboxylate (926 mg, 5 mmol), DIPEA (1.94 g, 15 mmol), EtOH (7.5 mL) and heated to 100¡ã C. for 10 minutes in a microwave oven, single node heating. Additional ethyl2-cyanoethanimidoate (252 mg, 4.5 mmol) and DIPEA (969 mg, 7.5 mmol) was added to each vial and the stirring was continued at r.t for 16 hours. LC-MS showed still some remaining tert-butyl piperidine-4-carboxylate and therfore ethyl2-cyanoethanimidoate (246 mg, 2.2 mmol) was added and the mixture was again heated to 100¡ã C. in a microwave oven for 20 minutes. The solutions from the vials was combined and used without further purification in the next step.
As the paragraph descriping shows that 138007-24-6 is playing an increasingly important role.
Reference£º
Patent; AstraZeneca AB; US2008/171732; (2008); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem