119515-38-7, sec-Butyl 2-(2-hydroxyethyl)piperidine-1-carboxylate is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Example 34 – 2-(1-sec-Butoxycarbony -2-piperidyl)acetic acid 41 Concentrated sulfuric acid (0.49 mL) was added dropwise to a solution of sodium dichromate (650 mg, 2.18 mmol) in water (3 mL) and the solution was then added dropwise to an ice- cooled solution of lcaridin (500 mg, 2.18 mmol) in acetone (30 mL). The reaction mixture was heated at 40 C for 16 hours, after which time TLC analysis showed complete consumption of the starting material. The reaction mixture was diluted with water (20 mL) then filtered and the acetone removed in vacuo. The aqueous phase was extracted with EtOAc (3 x 25 mL) and washed with brine (2 x 50 mL) before being dried over MgS04 and the solvent removed in vacuo. The resulting solid was washed successively with EtOAc, hexanes then DCM and the solvent removed in vacuo. Water (15 mL) was added to the residue and extracted with DCM (3 x 10 mL) before being dried over MgS04 and the solvent removed in vacuo to afford the product as a colourless oil (487 mg, 92%). NMR deltaEta (CDCIs, 300 MHz): 4.73 – 4.66 (m, 2H), 4.00 – 3.95 (m, 1 H), 2.80 – 2.71 (m, 1 H), 2.63 – 2.47 (m, 2H), 1.60 – 1.33 (m, 8H), 1.15 – 1.11 (m, 3H), 0.85 – 0.81 (m, 3H). ESI-MS 537.3 – [M2Na]+., 119515-38-7
As the paragraph descriping shows that 119515-38-7 is playing an increasingly important role.
Reference£º
Patent; REDX PHARMA LIMITED; THOMPSON, William; JACKSON, Peter; LINDSAY, Derek; SCREEN, Thomas; MOLTON, Benjamin; URCH, Christopher; WO2013/136073; (2013); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem