118511-81-2, 1-(Piperidin-4-yl)-1H-indole is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
PREPARATION 4 1-[(1-N-Cyclopropylmethyl)-piperidine-4-yl]-indole To a solution of 4-(1-indolyl)-piperidine (0.6 g, 3 mmol) in dry ethanol (4 mL) was added anhydrous potassium carbonate (680 mg, 4.9 mmol). After 15 minutes, bromomethylcyclopropane (0.29 mL, 4.5 mmol) was added and stirring was continued over night. Additional potassium carbonate (0.22 g) and bromomethylcyclopropane (0.14 mL) was added. After 3 hours, the reaction mixture was quenched with water and extracted with ethyl acetate (3*). The combined organic phases were washed with water, dried, evaporated, and purified by column chromatography on silica gel eluding with methylene chloride/ethanol (98:2). Evaporation of the eluding solvent gave the title compound. 480 mg (63% yield).
118511-81-2, As the paragraph descriping shows that 118511-81-2 is playing an increasingly important role.
Reference：
Patent; Eli Lilly and Company; US5545636; (1996); A;,
Piperidine – Wikipedia
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