Analyzing the synthesis route of 1062580-52-2

As the paragraph descriping shows that 1062580-52-2 is playing an increasingly important role.

1062580-52-2, (3R,4R)-1-Benzyl-N,4-dimethylpiperidin-3-amine dihydrochloride is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

After (3R,4R)-l-ber)_^l-N,4-dimemylpiperidin-3-amine dihydrochloride (195.5 mg, 0.6 mmol) was dissolved in ethanol(5.0 ml), N,N-diisopropyletheylamine (350.8 2.0 mmol) was added dropwise thereto, and the mixture was stirred at room temperature for 10 minutes. 3,4,6-tric oro-lH-pyrazolo[3,4-d]pyrirnidine (50.0 mg, 0.4 mmol) was added, the temperature was raised to 100 C and stirring was further carried out for 2 hours. Thereafter, the solution was filtered under reduced pressure, and the obtained residue was isolated by column chromatography to obtain a title compound (45.1 mg , yield: 24.9%). NMR (500MHz, CD3OD) delta 7.32-7.21(m, 5H), 5.11-5.07(m, 1H), 3.69(s, 3H), 3.52-3.48(m, 2H), 2.98-2.70(m, 2H), 2.62-2.59(m, 1H), 2.25-2.14(m, 2H), 1.73-1.72(m, 2H), 0.95-0.94(d, J= 5 Hz, 3H), 1062580-52-2

As the paragraph descriping shows that 1062580-52-2 is playing an increasingly important role.

Reference:
Patent; DAEWOONG PHARMACEUTICAL CO., LTD.; KIM, In Woo; HAN, Mi Ryeong; YOO, Jakyung; OH, Yun Ju; KIM, Ji Duck; KIM, Nam Youn; JUN, Sun Ah; LEE, Jun Hee; PARK, Joon Seok; (197 pag.)WO2018/4306; (2018); A1;,
Piperidine – Wikipedia
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