10338-57-5, 4-(Piperidin-1-yl)benzaldehyde is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a stirred solution of2-acetylbenzofuran (1) (1.6 g, 10 mmol) and 4-piperidinylbenzaldehyde(2) (1.89 g, 10 mmol) in ethanol (30 mL), 10%aqueous sodium hydroxide (10 mL) was added portion-wise atroom temperature for 10 min, the reaction mixture was furtherstirred for 3 h. The resulting solid was filtered, washed withwater, dried and crystallized from EtOH/DMF to afford chalcone3. orange powder; 85% yield; mp 178-179C; 1H-NMR(DMSO-d6) delta: 1.40-1.56 (6H, m, piperidine H), 2.98-3.26(4H, m, piperidine H), 6.70-6.72 (1H, d, J=14.0 Hz, -CO-CH=), 6.88-6.92 (2H, d, J=14.0 Hz, Ar-H), 7.52-7.54 (1H,d, J=14 Hz,=CH-Ar), 7.61-7.82 (6H, m, Ar-H), 8.16 (1H, s,benzofuran H). IR (KBr) cm-1: 3099 (CH-Ar), 1648 (C=O),1578 (CH olefinic). MS m/z: 331 (M+, 100), 330 (68), 274 (26),247 (28), 214 (56), 186 (27), 145 (87), 117 (7). Anal. Calcd forC22H21NO2: C, 79.73; H, 6.39; N, 4.23. Found: C, 79.56; H,6.21; N, 4.17., 10338-57-5
10338-57-5 4-(Piperidin-1-yl)benzaldehyde 291354, apiperidines compound, is more and more widely used in various fields.
Reference：
Article; Nassar, Ekhlass; El-Badry, Yaser Abdel-Moemen; Kazaz, Hagar El; Chemical and Pharmaceutical Bulletin; vol. 64; 6; (2016); p. 558 – 563;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem