Amani, Javad; Molander, Gary A. published the artcile< Direct Conversion of Carboxylic Acids to Alkyl Ketones>, Reference of 180181-05-9, the main research area is ketone preparation photoredox synergistic catalytic coupling carboxylic acid alkyltrifluoroborate; synergistic photoredox nickel catalytic coupling carboxylic acid alkyltrifluoroborate.
An efficient and mild method for acyl-Csp3 bond formation based on the direct conversion of carboxylic acids has been established. This protocol is enabled by the synergistic, Ir-photoredox/nickel catalytic cross-coupling of in situ activated carboxylic acids and alkyltrifluoroborates. This versatile method is amenable to the cross-coupling of structurally diverse carboxylic acids with various potassium alkyltrifluoroborates, affording the corresponding ketones with high yields. In this operationally simple cross-coupling protocol, aliphatic ketones are obtained in one step from bench stable, readily available carboxylic acids.
Organic Letters published new progress about Carboxylic acids Role: RCT (Reactant), RACT (Reactant or Reagent) (activated). 180181-05-9 belongs to class piperidines, and the molecular formula is C22H23NO4, Reference of 180181-05-9.
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem