Computational note on IR and Raman spectra of neutral and protonated forms of Aripiprazole (Abilify) and its metabolite Dehydroaripiprazole was written by Alparone, Andrea;Millefiori, Salvatore. And the article was included in Journal of Molecular Structure: THEOCHEM in 2010.Application of 129722-25-4 This article mentions the following:
ν(N-H+) peaks in mono- and di-protonated aripiprazole (AP), and the intense ν(ring(B,C)) Raman transitions in AP main metabolite, dehydroaripiprazole (DAP), are helpful vibrational markers to distinguish, resp., protonated and metabolite species from the parent AP drug. In the experiment, the researchers used many compounds, for example, 7-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butoxy)quinolin-2(1H)-one (cas: 129722-25-4Application of 129722-25-4).
7-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)butoxy)quinolin-2(1H)-one (cas: 129722-25-4) belongs to piperazine derivatives. Piperazine belongs to the family of medicines called anthelmintics. Piperazine is an anthelminthic especially useful in the treatment of partial intestinal obstruction caused by Ascaris worms, which is a condition primarily seen in children. Piperazine hydrate and piperazine citrate are the main anthelminthic piperazines.Application of 129722-25-4
Referemce:
Piperazine – Wikipedia,
Piperazines – an overview | ScienceDirect Topics