New Gly-Pro-Glu (GPE) analogs: Expedite solid-phase synthesis and biological activity was written by Alonso De Diego, Sergio A.;Gutierrez-Rodriguez, Marta;Perez de Vega, M. Jesus;Casabona, Diego;Cativiela, Carlos;Gonzalez-Muniz, Rosario;Herranz, Rosario;Cenarruzabeitia, Edurne;Frechilla, Diana;Del Rio, Joaquin;Luisa Jimeno, M.;Teresa Garcia-Lopez, M.. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2006.Recommanded Product: (S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidine-2-carboxylic acid The following contents are mentioned in the article:
A suitable solid-phase approach, based on Fmoc/tBu methodol. and on the use of 2-chlorotrityl resin, allowed a rapid and efficient preparation of new GPE analogs. Most of the synthesized tripeptides displayed glutamate receptor binding affinity comparable to that of GPE, but only a few derivatives showed significant neuroprotective activity. This study involved multiple reactions and reactants, such as (S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidine-2-carboxylic acid (cas: 86069-86-5Recommanded Product: (S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidine-2-carboxylic acid).
(S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidine-2-carboxylic acid (cas: 86069-86-5) belongs to piperidine derivatives. Piperidine is a metabolite of cadaverine, a polyamine found in the human intestine. Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol.Recommanded Product: (S)-1-(((9H-Fluoren-9-yl)methoxy)carbonyl)piperidine-2-carboxylic acid
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem