On April 30, 2012, Ali, Imran; Gupta, Vinod K.; Singh, Prashant; Negi, Uma published an article.SDS of cas: 39512-49-7 The title of the article was Monitoring of haloperidol and its metabolites in plasma by SPE-RP-TLC spectrometry. And the article contained the following:
We describe a simple and inexpensive SPE-RP-TLC method for the monitoring and anal. of haloperidol and its metabolites in plasma. Anal. was carried out on RP-TLC plates containing C18 silica gel using methanol having 0.001% diethylamine as a mobile phase. The chromatograms were developed up to 10 cm for 65 min at 28 ± 10°C. Detection of haloperidol and its metabolites was done by placing the dried plates in normal glass iodine chamber. The quant. anal. of haloperidol and its metabolites were carried out by using UV-visible spectroscopy at 230 nm. RF values of haloperidol, metabolite I, metabolite II, and metabolite III in plasma samples were 0.22, 0.06, 0.16, and 0.87, resp., and their percentage recoveries were 85.0, 88.0, 87.0, and 77.0, resp. The detection limit of RP-TLC method for haloperidol was 1.0 mg mL-1 and for all the three metabolites I, II, III was 0.8 mg mL-1. The results show that the developed method may be used for higher recovery of drugs under consideration from biol. samples. The experimental process involved the reaction of 4-(4-Chlorophenyl)piperidin-4-ol(cas: 39512-49-7).SDS of cas: 39512-49-7
The Article related to biomonitoring haloperidol metabolite solid phase extraction reverse phase tlc, Pharmacology: Drug Metabolism and other aspects.SDS of cas: 39512-49-7
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Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem