Abd Rabo Moustafa, Mahmoud M. et al. published their research in Organic Letters in 2010 | CAS: 33439-27-9

1-Tosylpiperidin-4-one (cas: 33439-27-9) belongs to piperidine derivatives. Piperidine and its derivatives have become increasingly popular in many synthetic schemes. Fluorinated piperidines are also the subject of continued interest in medicinal chemistry, for example in the synthesis of selective dipeptidyl peptidase II (DPP II) inhibitors. Piperidine derivatives are also used in solid-phase peptide synthesis (SPPS) and many degradation reactions.HPLC of Formula: 33439-27-9

Synthesis of 5-Azaindoles via a Cycloaddition Reaction between Nitriles and Donor-Acceptor Cyclopropanes was written by Abd Rabo Moustafa, Mahmoud M.;Pagenkopf, Brian L.. And the article was included in Organic Letters in 2010.HPLC of Formula: 33439-27-9 This article mentions the following:

A new method for the synthesis of 5-azaindole derivatives, e.g. I, is reported. A [3+2] dipolar cycloaddition between nitriles and a 3,4-cyclopropanopiperidine II followed by SeO2 oxidation affords the target compounds in moderate to excellent yields. The divergent nature and cost effectiveness of this method makes it very suitable for combinatorial applications in the pharmaceutical industry. In the experiment, the researchers used many compounds, for example, 1-Tosylpiperidin-4-one (cas: 33439-27-9HPLC of Formula: 33439-27-9).

1-Tosylpiperidin-4-one (cas: 33439-27-9) belongs to piperidine derivatives. Piperidine and its derivatives have become increasingly popular in many synthetic schemes. Fluorinated piperidines are also the subject of continued interest in medicinal chemistry, for example in the synthesis of selective dipeptidyl peptidase II (DPP II) inhibitors. Piperidine derivatives are also used in solid-phase peptide synthesis (SPPS) and many degradation reactions.HPLC of Formula: 33439-27-9

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem