A new application about tert-Butyl 4-formylpiperidine-1-carboxylate

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Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， SDS of cas: 137076-22-3, Which mentioned a new discovery about 137076-22-3

The first intermolecular carbonyl arylations via transfer hydrogenative reductive coupling are described. Using rhodium catalysts modified by tBu2PMe, sodium formate-mediated reductive coupling of aryl iodides with aldehydes occurs in a chemoselective fashion in the presence of protic functional groups and lower halides. This work expands the emerging paradigm of transfer hydrogenative coupling as an alternative to pre-formed carbanions or metallic reductants in C=X addition.

Because enzymes can increase reaction rates by enormous factors and tend to be very specific, SDS of cas: 137076-22-3, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 137076-22-3

Reference：
Piperidine – Wikipedia,
Piperidine | C5H16243N – PubChem