A new application about 218780-53-1

Because enzymes can increase reaction rates by enormous factors and tend to be very specific, name: 1-(Methylsulfonyl)piperidin-4-one, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 218780-53-1

Chemistry is the experimental and theoretical study of materials on their properties at both the macroscopic and microscopic levels.In a patent， name: 1-(Methylsulfonyl)piperidin-4-one, Which mentioned a new discovery about 218780-53-1

A crystal structure of 1 bound to a Cys25Ser mutant of cathepsin S helped to elucidate the binding mode of a previously disclosed series of pyrazole-based CatS inhibitors and facilitated the design of a new class of arylalkyne analogs. Optimization of the alkyne and tetrahydropyridine portions of the pharmacophore provided potent CatS inhibitors (IC50 = 40-300 nM), and an X-ray structure of 32 revealed that the arylalkyne moiety binds in the S1 pocket of the enzyme.

Because enzymes can increase reaction rates by enormous factors and tend to be very specific, name: 1-(Methylsulfonyl)piperidin-4-one, typically producing only a single product in quantitative yield, they are the focus of active research.you can also check out more blogs about 218780-53-1

Reference：
Piperidine – Wikipedia,
Piperidine | C5H10691N – PubChem