A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, Formula: C11H15N, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 3466-80-6, Name is 2-Phenylpiperidine, molecular formula is C11H15N. In a Article, authors is Abboud, Khalil A.£¬once mentioned of 3466-80-6
A Selenourea-Thiourea Br¡ãnsted Acid Catalyst Facilitates Asymmetric Conjugate Additions of Amines to alpha,beta-Unsaturated Esters
beta-Amino esters are obtained with high levels of enantioselectivity via the conjugate addition of cyclic amines to unactivated alpha,beta-unsaturated esters. A related strategy enables the kinetic resolution of racemic cyclic 2-arylamines, using benzyl acrylate as the resolving agent. Reactions are facilitated by an unprecedented selenourea-thiourea organocatalyst. As elucidated by DFT calculations and 13C kinetic isotope effect studies, the rate-limiting and enantiodetermining step of the reaction is the protonation of a zwitterionic intermediate by the catalyst. This represents a rare case in which a thiourea compound functions as an asymmetric Br¡ãnsted acid catalyst.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 3466-80-6, help many people in the next few years.Formula: C11H15N
Reference£º
Piperidine – Wikipedia,
Piperidine | C5H9308N – PubChem