Product Details of 1445-73-4In 2020 ,《Construction and bioimaging application of novel indole heptamethine cyanines containing functionalized tetrahydropyridine rings》 appeared in Journal of Materials Chemistry B: Materials for Biology and Medicine. The author of the article were Ma, Xiaoxie; Zhang, Chen; Feng, Lan; Liu, Sheng Hua; Tan, Ying; Yin, Jun. The article conveys some information:
IR780 as a com. available dye with near-IR emission has been extensively applied in fluorescent probes and bioimaging. In this work, to further intensify the optical behavior, a tetrahydropyridine ring was used to replace the cyclohexene ring at the center of IR780, forming a cyanine dye Cy-NH with near-IR emission. Photophys. properties demonstrated that Cy-NH exhibits good optical performance. In particular, Cy-NH contains two functional reaction sites (e.g. Cl and NH sites on the tetrahydropyridine ring) and can be used to construct functional cyanine dyes. Investigation on imaging showed that these cyanines can be used as near-IR fluorescent imaging agents in living cells and in vivo. In addition to this study using 1-Methyl-4-piperidone, there are many other studies that have used 1-Methyl-4-piperidone(cas: 1445-73-4Product Details of 1445-73-4) was used in this study.
1-Methyl-4-piperidone(cas: 1445-73-4) is a member of piperidine. Piperidine-containing compounds are also frequently employed in synthesis as ligands or auxiliaries. Accordingly, many efforts have been devoted to the development of novel methods for the synthesis of these compounds over the years.Product Details of 1445-73-4
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem