Shalini team published research on Journal of Molecular Structure in 2022 | 5382-16-1

Synthetic Route of 5382-16-1, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., 5382-16-1.

Piperidine was first reported in 1850 by the Scottish chemist Thomas Anderson and again, independently, in 1852 by the French chemist 5382-16-1, formula is C5H11NO, Name is 4-Piperidinol. Auguste Cahours, who named it. Both of them obtained piperidine by reacting piperine with nitric acid. Synthetic Route of 5382-16-1.

Shalini;Lata, Shubham;Saha, Sourav Taru;Kaur, Mandeep;Awolade, Paul;Ebenezer, Oluwakemi;Singh, Parvesh;Kumar, Vipan research published 《 Tetrahydro-β-carboline-naphthalimide hybrids: synthesis and anti-proliferative evaluation on estrogen-dependent and triple-negative breast cancer cells》, the research content is summarized as follows. A series of tetrahydro-β-carboline-naphthalimide hybrids I [X = (CH2)n; n = 1, 2, 3; R = H, Br, 1-piperidinyl, 4-morpholinyl, 4-hydroxy-1-piperidinyl, 4-(2-hydroxyethyl)-1-piperazinyl] were designed and synthesized via an amide coupling reaction. The obtained hybrids were evaluated for their growth inhibitory potential against MCF7 and MDA-MB-231 breast cancer cell lines using MTT assay. Three of the promising hybrids with IC50s < 43μM were further scrutinized for their interactions with selected target, i.e. estrogen receptor ERα. The designed template showed a decent growth inhibitory potential on breast cancer cells with high safety profile and hence, the present manuscript reveals the success rate of hybridization technique in clubbing two individual anti-cancer cores, i.e. tetrahydro-β-carboline and naphthalimide.

Synthetic Route of 5382-16-1, 4-Hydroxypiperidine is a molecule with a carbonyl group. It is the most active and selective CCR5 receptor antagonist that has been studied to date. 4-Hydroxypiperidine inhibits HIV infection by preventing the binding of HIV to its receptor on the surface of white blood cells, thereby preventing it from entering these cells. 4-Hydroxypiperidine also acts as an anti-inflammatory agent in chronic bronchitis patients, due to its ability to inhibit prostaglandin synthesis. The chemical ionization mass spectra of this molecule show peaks for methyl ethyl, malic acid, and hydroxyl groups. These properties make 4-hydroxypiperidine a useful candidate for drug development against inflammatory diseases and several cancers.
The molecular structure, vibrational spectra, NBO and UV-spectral analysis of 4-Hydroxypiperidine have been studied. The compounds with a substituted 4-piperidinol core have been found to be potent antagonists of the human H receptor., 5382-16-1.

Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem