Piperidine the name comes from the genus name Piper, which is the Latin word for pepper. 2403-88-5, formula is C9H19NO, Name is 2,2,6,6-Tetramethyl-4-piperidinol. Although piperidine is a common organic compound, it is best known as a representative structure element within many pharmaceuticals and alkaloids, such as natural-occurring solenopsins. Computed Properties of 2403-88-5.
Kolkman, Annemieke;Vughs, Dennis;Sjerps, Rosa;Kooij, Pascal J. F.;van der Kooi, Margo;Baken, Kirsten;Louisse, Jochem;de Voogt, Pim research published 《 Assessment of Highly Polar Chemicals in Dutch and Flemish Drinking Water and Its Sources: Presence and Potential Risks》, the research content is summarized as follows. Highly polar chems. are mobile in an aqueous environment. Anal. methods for these compounds in water are lacking. A combined target/nontarget screening method based on hydrophilic interaction LC coupled to high-resolution MS was developed. Thirty-two highly polar chems. (including melem and melam) can thus be quant. measured in surface water and drinking water, and the MS data can be screened for unknown compounds This is the first time a method for the determination of melem and melam in water has been described. The method is complementary to existing target and nontarget methods for less polar substances and can be applied for (drinking) water quality assessment. In a screening study in The Netherlands and Flanders, 12 of the 32 compounds were encountered in groundwater, surface water, and drinking water at levels between 0.01 and 4.2μg/L. Concentrations in drinking water were compared with (provisional) guideline values to assess whether these may pose a concern for human health. In one drinking water sample, the concentration of dichloroacetic acid exceeded the provisional guideline value, indicating that health effects cannot be excluded on the basis of lifetime exposure. For most chems., reliable drinking water guideline values could not be derived due to the limited available of toxicity data. The assessment of drinking water quality based on a new anal. method is presented along with derivation of guideline values for highly polar chems.
Computed Properties of 2403-88-5, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., 2403-88-5.
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem