Industrially, piperidine is produced by the hydrogenation of pyridine, usually over a molybdenum disulfide catalyst: C5H5N + 3 H2 → C5H10NH. 2403-88-5, formula is C9H19NO, Name is 2,2,6,6-Tetramethyl-4-piperidinol. Pyridine can also be reduced to piperidine via a modified Birch reduction using sodium in ethanol. Synthetic Route of 2403-88-5.
Kang, Seokwoo;Jeong, Jinwook;Kim, Beomjin;Park, Young Il;Noh, Seung Man;Park, Jongwook research published 《 New optimized triazene radical initiators for thermal polymerization》, the research content is summarized as follows. New phenyl-triazine-containing thermal radical initiators (TRIs), namely 3,3-dimethyl-1-phenyltriazene (BTAM), 3,3-diethyl-1-phenyltriazene (BTAE), 2,2,6,6-tetramethyl-1-(phenyldiazenyl)piperidine (BTACM), 2,2,6,6-tetramethyl-1-(phenyldiazenyl)piperidin-4-ol (BTACH-OH), and 2,2,6,-tetramethyl-1-(phenyldiazenyl)piperidin-4-ol (BTACM-OH), were designed and synthesized for use in radical polymerization The method used to synthesize the initiators was simple, and the synthesized initiators did not change the color of the polymer. For these five new initiators as well as four related previously designed ones, the polymerization conversion rate was in each case over 92%. BTACM, which also included a six-membered aliphatic ring substituted with two di-Me groups, showed a polymerization time 81.9% less than that without initiator and showed according to DSC experiments the lowest peak polymerization temperature of 137°C. These results represent a new promising thermal initiator system expected to be effective for various applications, especially those involving polymer coating.
2403-88-5, 2,2,6,6-Tetramethyl-4-piperidinol(TEMPO) is a useful research compound. Its molecular formula is C9H19NO and its molecular weight is 157.25 g/mol. The purity is usually 95%.
TEMPO is an intermediate used in the preparation of Piperidinyloxy free radical derivatives.
TEMPO is an organic compound that acts as a radical scavenger. It is stable in the presence of water and air and can be used for the inhibition of bacterial growth. TEMPO reacts with reactive intermediates to form non-reactive substances and terminate chain reactions. This process is optimal at temperatures between 0°C and 40°C and pH values between 3.5 and 7.5. TEMPO has been shown to inhibit the growth of bacteria by reacting with reactive molecules such as amines, chlorides, or low energy radicals in aqueous solution. TEMPO also has genotoxic activity that inhibits DNA synthesis in bacterial cells through oxidation of guanine residues on DNA molecules., Synthetic Route of 2403-88-5
Referemce:
Piperidine – Wikipedia,
Piperidine | C5H11N – PubChem