The preparation of ester heterocycles mostly uses heteroatoms as nucleophilic sites, which are achieved by intramolecular substitution or addition reactions. Compound: Tris(3,5-bis(trifluoromethyl)phenyl)phosphine( cas:175136-62-6 ) is researched.Safety of Tris(3,5-bis(trifluoromethyl)phenyl)phosphine.Koeken, Ard C. J.; van Vliet, Michiel C. A.; van den Broeke, Leo J. P.; Deelman, Berth-Jan; Keurentjes, Jos T. F. published the article 《Hydroformylation of 1-octene in supercritical carbon dioxide and organic solvents using trifluoromethyl-substituted triphenylphosphine ligands》 about this compound( cas:175136-62-6 ) in Advanced Synthesis & Catalysis. Keywords: hydroformylation octene supercritical carbon dioxide trifluoromethyl triphenylphosphine ligand. Let’s learn more about this compound (cas:175136-62-6).
Two different in situ prepared catalysts generated from Rh(CO)2acac and trifluoromethyl-substituted triphenylphosphine ligands have been evaluated for their activity and selectivity in the hydroformylation of 1-octene. The solvents used were supercritical carbon dioxide, hexane, toluene, and perfluoromethylcyclohexane. The highest value for the turnover frequency, 9820 mol1-octene molRh-1 h-1, has been obtained in supercritical carbon dioxide using the ligand P[C6H3(CF3)2-3,5]3. For both supercritical carbon dioxide and hexane employing the ligand P(C6H4CF3-3)3, a selectivity towards the linear aldehyde product, nonanal, and an n:iso ratio of 79.3% and 4.6-4.8 have been obtained, resp. These values are significantly higher than those obtained with triphenylphosphine as ligand (nonanal: 74-76%, n:iso: 3.1-3.3). An increase in trifluoromethyl substitution on the tri-Ph ligand results in an increase in the 1-octene conversion rate, an increase in the n:iso ratio and a decrease in the overall selectivity towards aldehydes. In terms of turn-over frequency and selectivity, the three ligands give comparable results in supercritical carbon dioxide and hexane. This leads to the conclusion that the properties of supercritical carbon dioxide as a solvent for hydroformylation can be better compared with those of hexane rather than with those of toluene.
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Piperidine – Wikipedia,
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