19099-93-5, 1-Cbz-Piperidin-4-one is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
490 g of ammonium carbonate and 70 g of potassium cyanide were added to the reaction flask,700 mL of water and 700 mL of ethanol were added. Finally, 100 g of 1-benzyloxycarbonyl-4-piperidone was added, heated to 60 C, and reacted till the inorganic salt dissolves completely. After a period of time there will be a lot of crystals appear, reacted for 24 hours, and cooled to room temperature. The reaction solution was filtered off and the cake was washed with 1000 mL of water. The filter cake was then added to a 2000 mL mixture of ethanol and water (V ethanol: V = 4: 1), heated to 50C after slow cooling, followed by recrystallization to give 130 g of compound 5.
19099-93-5, The synthetic route of 19099-93-5 has been constantly updated, and we look forward to future research findings.
Reference：
Patent; Henan Normal University; Mao Longfei; Jia Shuhong; Li Wei; Wu Doucan; Dong Wenpei; Shen Jiaxuan; Jiang Tao; Xu Guiqing; Jiang Yuqin; (9 pag.)CN105017252; (2017); B;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem