118133-15-6, 1-(Ethoxycarbonyl)piperidine-4-carboxylic acid is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
A 100 mL round bottom flask was taken and Intermediate 1, 7.434 g (37 mmol) was added. 18 mL dichloromethane, cooled to 0 C, triethylamine was added 12.8 mL (92.5 mmol), stirred for 15 minutes, Ethyl chloroformate 5.3mL (55.5mmol) was added stirred for 30 minutes, ethanol 20mL was added and stirred overnight at room temperature. After completion of the reaction, 1M sodium hydroxide was added 30mL, extracted with dichloromethane burning (30 ml x 3), combined with dichloromethane. It was washed with saturated brine, dried over anhydrous MgSO4, filtered and rotary evaporation done 78% as a pale yellow liquid., 118133-15-6
118133-15-6 1-(Ethoxycarbonyl)piperidine-4-carboxylic acid 6618886, apiperidines compound, is more and more widely used in various fields.
Reference：
Patent; Kunming Xianghao Technology Co., Ltd.; Luo Huairong; Hong Xuechuan; Zhu Xi; Zhu Jinmei; Wu Guisheng; Deng Zixin; Zhu Yingmin; Lu Yungang; Deng Ke; Qu Chunrong; (25 pag.)CN103694242; (2016); B;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem