Analyzing the synthesis route of 138022-04-5

138022-04-5, As the paragraph descriping shows that 138022-04-5 is playing an increasingly important role.

138022-04-5, tert-Butyl methyl(piperidin-4-ylmethyl)carbamate is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

Step A: tert-Butyl ({l-[(2i?)-2-Hydroxy-2-(4-methyl-l-oxo-l,3-dihydro-2-benzofuran-5- yl)ethyllpiperidin-4-yl|methyl)methylcarbamate A solution of 4-methyl-5-[(2i?)-oxiran-2-yl]-2-benzofuran-l(3H)-one (76 mg, 0.40 mmol) in 2 mL of ethanol was added to tert-butyl methyl(piperidin-4-ylmethyl)carbamate (91mg, 0.40 mmol). The reaction mixture was heated at 140C in the microwave for 55 minutes. The solvents were removed in vacuo to provide tert-butyl ({l-[(2i?)-2-hydroxy-2-(4-methyl-l-oxo-l,3- dihydro-2-benzofuran-5-yl)ethyl]piperidin-4-yl}methyl)methylcarbamate which was used directly in the next step without further purification.

138022-04-5, As the paragraph descriping shows that 138022-04-5 is playing an increasingly important role.

Reference:
Patent; MERCK SHARP & DOHME CORP.; WALSH, Shawn; PASTERNAK, Alexander; CATO, Brian; FINKE, Paul, E.; FRIE, Jessica; FU, Qinghong; KIM, Dooseop; PIO, Barbara; SHAHRIPOUR, Aurash; SHI, Zhi-Cai; TANG, Haifeng; WO2013/39802; (2013); A1;,
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