Analyzing the synthesis route of 20691-89-8

The synthetic route of 20691-89-8 has been constantly updated, and we look forward to future research findings.

20691-89-8, 1-Methyl-4-piperidinemethanol is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

20691-89-8, To a solution of OXO-THIOPHEN-2-YL-ACETYL chloride (31. 5 mmol) at 0 to 5OC in chloroform (60 ml) is added a solution of (1-METHYL-PIPERIDIN-4-YL)-METHANOL (4.07 g, 31.5 mmol) in chloroform (60 ml), dropwise maintaining the temperature below 5C. The resulting mixture is stirred for 2 hours at room temperature. Washing with 10% potassium carbonate solution, water and then drying over magnesium sulphate, filtration and evaporation gives the title compound.

The synthetic route of 20691-89-8 has been constantly updated, and we look forward to future research findings.

Reference：
Patent; NOVARTIS AG; NOVARTIS PHARMA GMBH; WO2005/815; (2005); A2;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem