10338-57-5, 4-(Piperidin-1-yl)benzaldehyde is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
General procedure: The synthesis of compounds 5, 14-23 and 26-31 follows a multi-component procedure described by Groebke et al.1 N-Cyclohexyl-2-(4-morpholinophenyl)imidazo[1,2-a]pyridin-3- amine 17: 0.30 g (3.1 mmol) 2-aminopyridine and 0.60 g (3.1 mmol) 4-morpholinobenzaldehyde were stirred with glacial acetic acid and 35 mL anhydrous MeOH, then 0.35 g (3.1 mmol) cyclohexyl isocyanide was added. After 18 h the reaction mixture was quenched with 5 mL 2N HCl to destroy the residual isocyanide. MeOH was removed under reduced pressure and 50 mL saturated NaHCO3 solution was added. The product was extracted with EtOAc (3 x 40 mL) and the solvent was removed under reduced pressure. The purification was completed by recrystallization from EtOAc/MeOH yielding 0.50 g (42.2%) yellow solid.
10338-57-5, The synthetic route of 10338-57-5 has been constantly updated, and we look forward to future research findings.
Reference：
Article; Hieke, Martina; Roedl, Carmen B.; Wisniewska, Joanna M.; La Buscato, Estel.; Stark, Holger; Schubert-Zsilavecz, Manfred; Steinhilber, Dieter; Hofmann, Bettina; Proschak, Ewgenij; Bioorganic and Medicinal Chemistry Letters; vol. 22; 5; (2012); p. 1969 – 1975;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem