4897-50-1, 4-Piperidinopiperidine is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Example 1.; Preparation of 1-chlorocarbonyl-4-piperidinopiperidine base (IRT-4):; Dissolving 4-piperdinoperidine (100g) in benzene (1580ml) under stirring for 15 to 30 minutes at room temperature, adding a solution of triphosgene (150g) in benzene (660 ml) over a period of 1 to 3 hours at a temperature of 20¡ã- 25¡ãC. Filtering the solid, washing it with benzene and drying, then dissolve the dried solid in chloroform (5900 ml) by stirring at room temperature for about 30 minutes. Charging aqueous sodium bicarbonate solution (400 ml), stirring and separating chloroform layer, washing the chloroform layer with water (1800 ml), separating chloroform layer anddistilling off chloroform under vacuum at a temperature up to below 45¡ãC to obtain 1-chlorocorbonyl-4-piperidopiperidine base (60 g).
4897-50-1, The synthetic route of 4897-50-1 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; SHILPA MEDICARE LIMITED; WO2006/16203; (2006); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem