135716-08-4, tert-Butyl 4-(2-ethoxy-2-oxoethylidene)piperidine-1-carboxylate is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
The above resulting product (639mg,2.4mmol) dissolved in 6ml of methanol, Underargon added the argon was replaced with hydrogen three times and reaction was carried out overnightin a hydrogenation apparatus (4 atm H2). The reaction solution was filteredthrough celite and washed with ethyl acetate. The filtrate was concentrated andseparated by column chromatography to give a white solid, 722 mg, 100percent yield. theabove resulting product(506mg,1.9mmol) dissolved in 10ml of ether, reaction was colled down to -20 ° C, added diisobutylaluminum hydride(1.0M,5mL,5mmol), reaction was carried out for 10 minutes until the starting material disappeared. Then Poured into saturated sodium potassium tartrate solution, stirred at room temperature for 3 hours to clarify the reaction mixture,the aqueous phase was extracted three times with ether and the organic phases were combined and washed with saturated NaClsolution and dried over Na2SO4, After Concentration, carriedout column chromatography separation to obtain a White solid, 368mg, yield 86percent.
135716-08-4, As the paragraph descriping shows that 135716-08-4 is playing an increasingly important role.
Reference：
Patent; Peking University; ZHANG, FENG YING; WANG, BIN; HUANG, BIN; JIA, YAN XING; (19 pag.)CN102952072; (2016); B;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem