Analyzing the synthesis route of 63921-23-3

The synthetic route of 63921-23-3 has been constantly updated, and we look forward to future research findings.

63921-23-3, 1-Phenylpiperidin-4-amine is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

63921-23-3, (1) Preparation of phenyl N-(1-phenyl-4-piperidyl)carbamate pyridine (24 muL) and phenyl chlorocarbonate (32 muL) were added to a solution of 1-phenyl-4-piperidylamine (35 mg) in tetrahydrofuran (1 ML), and the mixture was stirred at room temperature for 12 hours.. The reaction mixture was poured into saturated aqueous sodium bicarbonate, and extracted with ethyl acetate.. The organic layer was dried over anhydrous magnesium sulfate and concentrated.. The residue was purified by column chromatography on silica gel (ethyl acetate/chloroform = 1/1) to give the title compound (37 mg).

The synthetic route of 63921-23-3 has been constantly updated, and we look forward to future research findings.

Reference:
Patent; BANYU PHARMACEUTICAL CO., LTD.; EP1415986; (2004); A1;,
Piperidine – Wikipedia
Piperidine | C5H11N – PubChem