Wu, P; Huang, W; Cheng, TJ; Lin, HX; Xu, H; Dai, HX in [Cheng, Tai-Jin; Xu, Hui; Dai, Hui-Xiong] Chinese Acad Sci, Shanghai Inst Mat Med, Key Lab Receptor Res, Shanghai 201203, Peoples R China; [Dai, Hui-Xiong] Peking Univ, State Key Lab Nat & Biomimet Drugs, Beijing 100191, Peoples R China; [Cheng, Tai-Jin; Dai, Hui-Xiong] Univ Chinese Acad Sci, Beijing 100049, Peoples R China; [Wu, Peng; Lin, Hai-Xia] Shanghai Univ, Innovat Drug Res Ctr, Dept Chem, Shanghai 200444, Peoples R China; [Huang, Wei] Nanchang Univ, Sch Pharm, Nanchang 330006, Jiangxi, Peoples R China published Copper-Catalyzed Oxalamide-Directed ortho-C-H Amination of Anilines with Alkylamines in 2020, Cited 56. HPLC of Formula: C7H13NO2. The Name is 1,4-Dioxa-8-azaspiro[4.5]decane. Through research, I have a further understanding and discovery of 177-11-7.
A copper-catalyzed oxalamide-directed ortho-C-H amination of anilines has been developed by using 1 atm of air as the sole oxidant. The protocol shows excellent functional group tolerance, and some heterocyclic amines including indole, benzothiophene, benzothiazole, quinoline, isoquinoline, and quinoxaline could be compatible in the reaction. The late-stage diversification of medicinal drugs demonstrates the synthetic utility of this protocol.
HPLC of Formula: C7H13NO2. About 1,4-Dioxa-8-azaspiro[4.5]decane, If you have any questions, you can contact Wu, P; Huang, W; Cheng, TJ; Lin, HX; Xu, H; Dai, HX or concate me.
Reference：
Piperidine – Wikipedia,
Piperidine | C5H7510N – PubChem