A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, Safety of 1-Ethyl-1-methyl-4-oxopiperidin-1-ium iodide, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 77542-18-8, Name is 1-Ethyl-1-methyl-4-oxopiperidin-1-ium iodide, molecular formula is C8H16INO. In a Article, authors is Wichmann, Juergen，once mentioned of 77542-18-8
The development of 8-(2,3,3a,4,5,6-hexahydro-1H-phenalenl-yl)-1-phenyl-1,3,8-triaza-spiro[4.5]de can-4-ones 3 starting from (RS)-8-acenaphten-1-yl-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one 1 is reported. The synthesis and the binding affinities at human OFQ and opioid (mu, chi, delta) receptors of the stereoisomers 3a-f are described. In vitro the most selective compound, (1S,3aS)-8-(2,3,3a,4,5,6-hexahydro-1H-phenalenl-yl)-1-phenyl-1,3,8-triaza-spi ro[4.5]decan-4-one 3c, was found to act as a full agonist at the OFQ receptor in the GTPgamma35S binding test. It turned out to be selective versus a variety of other neurotransmitter systems. When tested in vivo following intraperitoneal injection, compound 3c was found to decrease neophobia in a novel environment and to exhibit dose-dependent anxiolytic-like effects in the elevated plus-maze procedure, thus confirming the effects observed following intracerebroventricular infusion of the OFQ peptide in rat. (C) 2000 Editions scientifiques et medicales Elsevier SAS.
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Reference：
Piperidine – Wikipedia,
Piperidine | C5H21715N – PubChem