A catalyst don’t appear in the overall stoichiometry of the reaction it catalyzes, Computed Properties of C12H14FNO, but it must appear in at least one of the elementary reactions in the mechanism for the catalyzed reaction. 56346-57-7, Name is (4-Fluorophenyl)(piperidin-4-yl)methanone, molecular formula is C12H14FNO. In a Article, authors is Zhu, Mei,once mentioned of 56346-57-7
Since dual inhibitors may yield lower toxicity and reduce the likelihood of drug resistance, as well as inhibitors of HIV-1 PR and RT constitute the core of chemotherapy for AIDS treatment, we herein designed and synthesized new coumarin derivatives characterized by various linkers that exhibited excellent potency against PR and a weak inhibition of RT. Among which, compounds 6f and 7c inhibited PR with IC50 values of 15.5 and 62.1 nM, respectively, and weakly affected also RT with IC50 values of 241.8 and 188.7 muM, respectively, showing the possibility in the future of developing dual HIV-1 PR/RT inhibitors. Creative stimulation for further research of more potent dual HIV-1 inhibitors was got according to the molecular docking studies.
I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 56346-57-7, help many people in the next few years.Computed Properties of C12H14FNO
Reference:
Piperidine – Wikipedia,
Piperidine | C5H15455N – PubChem