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The present invention provides compounds of Formula I (I) and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt and water retention.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Recommanded Product: 124443-68-1, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 124443-68-1, in my other articles.
Reference：
Piperidine – Wikipedia,
Piperidine | C5H20152N – PubChem