39945-51-2, Benzyl 3-(hydroxymethyl)piperidine-1-carboxylate is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
39945-51-2, Example 70A Benzyl 3-[(vinyloxy)methyl]piperidine-1-carboxylate At RT, 23 ml (241 mmol) of ethyl vinyl ether were added to 321 mg (0.65 mmol) of chloro(triphenylphosphine)gold(I) and 108 mg of silver(I) acetate. After 10 min of stirring, 6.00 g (24.07 mmol) of benzyl 3-(hydroxymethyl)piperidine-1-carboxylate were added. The mixture was stirred at 50 C. for 5 h. This was followed by concentration under reduced pressure. The crude product was purified by chromatography on silica gel (mobile phase: cyclohexane/ethyl acetate gradient 100:0-100:1-20:1-10:1). This gave 4.40 g of product (66% of theory). LC-MS[Method 1]: Rt=1.15 min; MS (ESI+): m/z=276 (M+H)+
39945-51-2 Benzyl 3-(hydroxymethyl)piperidine-1-carboxylate 2776577, apiperidines compound, is more and more widely used in various fields.
Reference£º
Patent; Bayer Pharma Aktiengesellschaft; BECKER-PELSTER, Eva Maria; BUCHGRABER, Philipp; BUCHMUeLLER, Anja; ENGEL, Karen; GNOTH, Mark Jean; HIMMEL, Herbert; KAST, Raimund; KELDENICH, Joerg; KLAR, Juergen; KNORR, Andreas; LANG, Dieter; LINDNER, Niels; SCHMECK, Carsten; SCHOHE-LOOP, Rudolf; TINEL, Hanna; TRUeBEL, Hubert; WUNDER, Frank; (97 pag.)US2016/318866; (2016); A1;,
Piperidine – Wikipedia
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