A new application about 1-Aminopiperidine

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Fumagillin, an irreversible inhibitor of MetAP2, has been shown to potently inhibit growth of malaria parasites in vitro. Here, we demonstrate activity of fumagillin analogs with an improved pharmacokinetic profile against malaria parasites, trypanosomes, and amoebas. A subset of the compounds showed efficacy in a murine malaria model. The observed SAR forms a basis for further optimization of fumagillin based inhibitors against parasitic targets by inhibition of MetAP2.

I hope this article can help some friends in scientific research. I am very proud of our efforts over the past few months and hope to 2213-43-6, help many people in the next few years.Quality Control of: 1-Aminopiperidine

Reference：
Piperidine – Wikipedia,
Piperidine | C5H966N – PubChem