896464-16-7,896464-16-7, tert-Butyl 2,7-diazaspiro[3.5]nonane-7-carboxylate is a piperidines compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Add to tert-butyl 2,7-azaspiro[3,5]nonane-7-carboxylate (226 mg, 1.0 mmol) at room temperature4-trifluoromethoxyacetophenone (204 mg, 1.0 mmol) andTetraisopropyl titanate (568 mg, 2.0 mmol) was reacted at 80 C overnight.After cooling to room temperature, sodium cyanoborohydride (188 mg, 3.0 mmol) was added to the mixture, and the mixture was reacted at 40 C for 2 hours.Work-up: extraction with water and extraction with dichloromethane (20 mL x 3).The organic layer was combined, dried over anhydrous magnesium sulfate and evaporated(Ethyl acetate: petroleum ether = 1 : 2) gave pale yellow oil (150 mg).
The synthetic route of 896464-16-7 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Chinese Academy Of Medical Sciences Pharmaceutical Bio-technology Institute; Liu Mingliang; Wang Apeng; Lv Kai; Tao Zeyu; Ma Chao; Han Bing; Ma Xican; Wang Aoyu; Xu Shijie; (23 pag.)CN110204546; (2019); A;,
Piperidine – Wikipedia
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