Related Products of 607354-69-8, Catalysts are substances that increase the reaction rate of a chemical reaction without being consumed in the process. 607354-69-8, Name is 1-(4-Trifluoromethylphenyl)piperidine-4-carboxylic acid, molecular formula is C13H14F3NO2. In a Article，once mentioned of 607354-69-8
KCNQ (Kv7) has emerged as a validated target for the development of novel anti-epileptic drugs. In this paper, a series of novel N-phenylbutanamide derivatives were designed, synthesized and evaluated as KCNQ openers for the treatment of epilepsy. These compounds were evaluated for their KCNQ opening activity in vitro and in vivo. Several compounds were found to be potent KCNQ openers. Compound 1 with favorable in vitro activity was submitted to evaluation in vivo. Results showed that compound 1 owned significant anti-convulsant activity with no adverse effects. It was also found to posses favorable pharmacokinetic profiles in rat. This research may provide novel potent compounds for the discovery of KCNQ openers in treating epilepsy.
Sometimes chemists are able to propose two or more mechanisms that are consistent with the available data. Related Products of 607354-69-8, If a proposed mechanism predicts the wrong experimental rate law, however, the mechanism must be incorrect.Welcome to check out more blogs about 607354-69-8, in my other articles.
Reference：
Piperidine – Wikipedia,
Piperidine | C5H22259N – PubChem