Synthetic Route of 135632-53-0, In heterogeneous catalysis, the catalyst is in a different phase from the reactants. At least one of the reactants interacts with the solid surface in a physical process called adsorption in such a way. 135632-53-0, name is tert-Butyl (piperidin-4-ylmethyl)carbamate. In an article,Which mentioned a new discovery about 135632-53-0
PKCtheta is a serine/threonine kinase involved in the regulation of IL2 production in T cells. It has recently become an attractive therapeutic target for a variety of immunological disorders. We describe the optimization of the enzymatic and cellular potency of a series of 5-vinyl-3-pyridinecarbonitrile inhibitors of PKCtheta. A binding model was developed that explains much of the SAR observed for this series, including the enzymatic potency observed for 19. An analysis of functional potency against various physiochemical parameters suggests that cellular potency is correlated with Log D7.4, but not with c Log P, PAMPA permeability, or TPSA.
Balanced chemical reaction does not necessarily reveal either the individual elementary reactions by which a reaction occurs or its rate law.135632-53-0. In my other articles, you can also check out more blogs about 135632-53-0
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Piperidine – Wikipedia,
Piperidine | C5H17337N – PubChem