Catalysts function by providing an alternate reaction mechanism that has a lower activation energy than would be found in the absence of the catalyst. In some cases, the catalyzed mechanism may include additional steps.In a article, 162167-97-7, molcular formula is C11H22N2O2, introducing its new discovery. Formula: C11H22N2O2
A series of trisubstituted pyrimidines were synthesized to improve aqueous solubility of our first TRPV1 clinical candidate (1; AMG 517), while maintaining potent TRPV1 inhibitory activity. Structure-activity and structure-solubility studies led to the identification of compound 26. The aqueous solubility of 26 (?200 mug/mL, 0.01 HCl; 6.7 mug/mL, phosphate buffered saline (PBS); 150 mug/mL, fasted-state simulated intestinal fluid (SIF)) was significantly improved over 1. In addition, compound 26 was found to be orally bioavailable (rat Foral = 24%) and had potent TRPV1 antagonist activity (capsaicin IC50 = 1.5 nM) comparable to that of 1.
One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Formula: C11H22N2O2, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 162167-97-7
Reference：
Piperidine – Wikipedia,
Piperidine | C5H17124N – PubChem