In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 24228-40-8, name is Ethyl N-benzylpiperidine-4-carboxylate, introducing its new discovery. Application In Synthesis of Ethyl N-benzylpiperidine-4-carboxylate
A continuous flow method for the direct conversion of alcohols to amines via a hydrogen borrowing approach is reported. The method utilises a low loading (0.5%) of a commercial catalyst system ([Ru(p-cymene)Cl2]2 and DPEPhos), reagent grade solvent and is selective for primary alcohols. Successful methylation of amines using methanol and the direct dimethylamination of alcohols using commercial dimethylamine solution are reported. The synthesis of two pharmaceutical agents Piribedil (5) and Buspirone (25) were accomplished in good yields employing these new methods.
The proportionality constant is the rate constant for the particular unimolecular reaction. the reaction rate is directly proportional to the concentration of the reactant. I hope my blog about 24228-40-8 is helpful to your research. Application In Synthesis of Ethyl N-benzylpiperidine-4-carboxylate
Reference：
Piperidine – Wikipedia,
Piperidine | C5H20705N – PubChem